Recitation_9-solutions-Simona

Recitation_9-solutions-Simona - TA: Simona Tescu RECITATION...

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TA: Simona Tescu RECITATION #9 Solutions Question 1)
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TA: Simona Tescu
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TA: Simona Tescu Question 2) Compound Effect on glycolysis Acts on: Glucose-6-P + Substrate for glycolysis Inhibits hexokinase ATP - Inhibits P-fructokinase and pyruvate kinase Activates Fructose-1,6- diphosphatase AMP + Activates P-Fructokinase and pyruvate kinase Inhibits Fructose-1,6-diphosphatase ADP + Activates P-Fructokinase Inhibits Fructose-1,6-diphosphatase Fructose-1,6-diphosphate + Activates pyruvate kinase Fructose-2,6-diphosphate + Activates P-fructokinase (allosteric activator) Inhibits fructose-1,6-diphosphatase Caffeine + Inhibits phosphodiesterase, maintaining cAMP increase in cAMP increase in active PKA Epinephrine + (hyperglycemic agent) ON glycolysis OFF gycogen synthesis cAMP + increase in cAMP increase in active PKA PKA + Activates glycogen phosphorylase more glucose-6-P produced Inhibits glycogen synthase
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This note was uploaded on 02/06/2009 for the course 7 7.05 taught by Professor Unknown during the Spring '09 term at MIT.

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Recitation_9-solutions-Simona - TA: Simona Tescu RECITATION...

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