Recitation__10_handout_Simona

Recitation__10_handout_Simona - -Inhibits citrate...

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TA: Simona Tescu 04/23/08 7.05 Recitation 1/4 RECITATION #10 Today we will cover: - TCA cycle and Pentose Metabolism GO TO FRIDAY MORNING PROBLEMS!!! Your chart should now contain: - Glycolysis - TCA cycle - Glyoxylate cycle - Other sugars (lactose, mannose, sucrose) converted to glycolysis intermediates - Gluconeogenesis (synthesis of glucose) - Glycogen synthesis and breakdown You should know the following mechanisms of the following enzymes : - Succinic tiokinase - Pyruvate carboxylase - Pyruvate decarboxylase - PEP carboxykinase - Transketolase - Transaldolase
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TA: Simona Tescu 04/23/08 7.05 Recitation 2/4 Regulation of the TCA cycle High ATP (low ADP and AMP) = excess of energy, stop breakdown of glucose and intermediates, promotes formation of glucose to store energy - Inhibits isocitrate dehydrogenase
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Unformatted text preview: -Inhibits citrate synthase -Activates pyruvate decarboxylase -Inhibits P-fructo kinase -Inhibits pyruvate oxidase particle Citrate -Inhibits P-fructo kinase AcetylCoA = more AcCoA is being present than it is metabolized through the TCA cycle, promotes gluconeogenesis to store energy -Activates pyruvate carboxylase -Activates PEP carboxykinase TA: Simona Tescu 04/23/08 7.05 Recitation 3/4 Question 1) Explain how a high concentration of ATP stimulates gluconeogenesis. Question 2) The glyoxylate cycle – only in bacteria and some plants TCA cycle problems Question 3) TA: Simona Tescu 04/23/08 7.05 Recitation 4/4 Question 4) Question 5) Pentose reactions -allows ribose to be synthesized (important for DNA and RNA) Question 6)...
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This note was uploaded on 02/06/2009 for the course 7 7.05 taught by Professor Unknown during the Spring '09 term at MIT.

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Recitation__10_handout_Simona - -Inhibits citrate...

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