MCB354FA08_ExamIBKEY - Multiple choice (51 points total, 3...

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1 Multiple choice (51 points total, 3 points each) For each question below, select one correct answer (A, B, C, D, or E) and fill in the bubble on the scantron. 1. The pH of a solution of 1M HCl is: A. 0 B. 0.1 C. 1 D. 10 E. -1 2. A major advance in the application of mass spectrometry to macromolecules came with the development of techniques to overcome which of the following problems? A. Macromolecules were insoluble in the solvents used in mass spectrometry. B. Mass spectrometric analysis of macromolecules were too complex to interpret. C. Mass spectrometric analysis involved molecules in the gas phase. D. Most macromolecules could not be purified to the degree required for mass spectrometric analysis. E. The specialized instruments required were prohibitively expensive. 3. Which of the following statements is true ? A. Collagen is a protein in which the polypeptides are mainly in the left handed α -helix conformation. B. Disulfide linkages are generally not present in keratin structure. C. Trp residues are particularly abundant in collagen. D. Silk fibroin is a protein in which the polypeptide is almost entirely in the α -helix. E. α -keratin is a protein in which the polypeptides are mainly in the α -sheet conformation. 4. For amino acids with neutral R groups, at any pH below the pI of the amino acid, the population of amino acids in solution will have: A. a net negative charge. B. a net positive charge. C. no charged groups. D. no net charge. E. positive and negative charges in equal concentration.
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2 5. Which of the following statements about aromatic amino acids is correct? A. All are strongly hydrophilic. B. Histidine’s ring structure results in it being categorized as aromatic or basic, depending on pH. C.
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This note was uploaded on 02/09/2009 for the course MCB 354 taught by Professor Spees during the Spring '09 term at University of Illinois, Urbana Champaign.

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MCB354FA08_ExamIBKEY - Multiple choice (51 points total, 3...

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