BIOS41_Lecture15_02202008

BIOS41_Lecture15_02202008 - 15_09_pore_transport.jpg...

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BIOS 41 Biology Core I: Cellular and Molecular Spring 2008 Professor J. A. Sands Lecture 15, February 20 Intracellular Compartments and Transport (Chapter 15, pages 497-511)
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15_01_organelles.EM.jpg
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15_02_cell_intestine.jpg Drawing of intestinal lining cell, showing membrane- enclosed organelles and ribosomes.
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15_03_ER_evolved.jpg How nucleus and endoplasmic reticulum may have evolved.
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15_05_import_proteins.jpg Organelles import proteins by one of three mechanisms.
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15_06_Signal_sequence.jpg Signal sequences direct proteins to the correct organelle.
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15_08_nuclear_pore.jpg Proteins enter the nucleus through nuclear pores.
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Unformatted text preview: 15_09_pore_transport.jpg Proteins bound for the nucleus are actively transported through nuclear pores. 15_10_unfolded_imprt.jpg Proteins unfold to enter mitochondria. 15_13_ER_signal_SRP.jpg An ER signal sequence and an SRP direct a ribosome to the ER membrane. 15_14_enters_lumen.jpg A soluble protein crosses the ER membrane and enters the lumen. 15_15_into_ER_membr.jpg A transmembrane protein is integrated into the ER membrane. 15_16_double_pass.jpg A double-pass membrane protein uses an internal start-transfer sequence to integrate into the ER membrane....
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