BIOS41_Lecture19_03122008

BIOS41_Lecture19_03122008 - molecules....

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BIOS 41 Biology Core I: Cellular and Molecular Spring 2008 Professor J. A. Sands Lecture 19, March 12 Energy Transformations and Mitochondria (Parts of Chapters 13&14)
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13_02_cell_metabolism.jpg Food molecules are broken down in three stages. Glycolysis results in 2 ATPs per glucose Complete oxidation of glucose to CO2 and water results in about 30 ATPs. Over 100 million ATPs can be produced and used per cell per minute.
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13_10_acetylCoA_prod.jpg Acetyl CoA is produced in mitochondria from molecules derived from sugars and fats. Fig. 3-37: Acetyl coenzyme A (CoA) is another important activated carrier molecule.
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13_11_citric_acid_cycle.jpg The citric acid cycle (Krebs cycle) catalyzes the complete oxidation of the carbon atoms of the acetyl groups of acetyl CoA. NADH, GTP, and FADH 2 are activated carrier
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Unformatted text preview: molecules. 13_17_final_oxidation .jpg A major portion of the energy released during an elaborate series of electron-transfers in the mitochondrial inner membrane is harnessed to drive the synthesis of ATP through the process of oxidative phosphorylation. The linkage of electron transport, proton pumping, and ATP synthesis is called “chemiosmotic coupling”. Electron micrograph of a mitochondrion. “A series of infoldings, known as cristae, greatly increase the surface area of the inner membrane.” “These folds provide a large surface on which ATP synthesis can take place.” Page 456. Summary of energy transformations in mitochondria. “The oxygen-requiring step of cellular respiration consumes nearly all the oxygen that we breathe.” Page 462...
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This note was uploaded on 04/19/2008 for the course BIOS 41 taught by Professor Sands during the Spring '08 term at Lehigh University .

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BIOS41_Lecture19_03122008 - molecules....

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