Chap 14 - Chap 14 Signal Transduction Secondary Messenger

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Chap 14 Signal Transduction Secondary Messenger systems- intracellular molecules that change in [] due to a response to  environmental signals, this conveys information to the cell 7TM receptors (seven transmembrane receptors) Includes   adrenergic receptors) β 1. Smell 2. Taste 3. Vision 4. Neurotransmission 5. Hormone secretion 2 types of messenger systems 1) cAMP first messenger binds to  7TM receptor receptor binds to  G  protein α G  protein α  activates  adenyl cyclase adenyl cyclase  converts  ATP to cAMP cAMP  binds and activates and activates  Protein Kinase A Protein Kinase A  catalyzes the transfer of  P from ATP  to protein Phosphoralation  activates protein and leads to cell response GTP departs  and binds when hormone receptor complex interacts with  G- Protein 2) IP3-DAG 
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First messenger (vasopressin)binds to 7TM receptor Receptor binds to 
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Chap 14 - Chap 14 Signal Transduction Secondary Messenger

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