Sleep Study Guide - Sleep Physiology Review Questions 1...

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Sleep Physiology Review Questions: 1. Provide a scientific definition of sleep. How does sleep differ physiologically from wakefulness or from coma? Sleep is a reversible behavioral state of perceptual disengagement from and unresponsiveness to the environment coma is pathophysiologic, not reversible, not recurrent 2. Define the stages of sleep in humans. Compare and contrast the key features of these stages (e.g., electroencephalographic characteristics, activation of important brain structures, autonomic activities, timing, and behaviors [such as dreaming and skeletal muscle activity]). The suprachiasmatic nuclei (SCN) is the master circadian pacemaker, controls melatonin production, and efferents to the thalamus, anterior hypothalamus, and preoptic area. The preoptic anterior hypothalamus (POAH) is responsible for regulating body temperature, and the POAH neuron firings increase during sleep, resulting in increased body temperature. Typical sleep cycle: Awake->REM->Stage 1->Stage 2->Stages 3&4 (not differentiated anymore?) Awake/relaxed: EEG shows alpha waves that are slower, have increased amplitude, and are more synchronous than beta waves. Awake/active: EEG shows beta waves that are high frequency, low amplitude, and very dyssynchronous (inconsistent patterns). Awake states are associated with increased sympathetic tone, metabolism, intermediate early gene expression, and optimal responsiveness to stimuli. Stages 1&2: Considered “light” sleep, EEG shows theta waves that are slower in frequency and greater in amplitude than alpha waves. Fewer than 20% of EEG waves will be delta waves in stage 2.
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  • Spring '16
  • Professor Smith
  • REM Sleep

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