Problem_Set_3_KEY - BIOL E-117 Genomics Fall 2007 Problem Set 3 KEY(15 points Due Nov 17 midnight Problem Set 3 These questions refer to the dataset

Problem_Set_3_KEY - BIOL E-117 Genomics Fall 2007 Problem...

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BIOL E-117 Genomics Fall 2007 Problem Set 3 KEY (15 points) Due Nov 17 midnight Problem Set 3 These questions refer to the dataset “Expression during the diauxic shift” available from the Saccharomyces Genome Database 1)(1 point) How many distinct mRNAs were tested in this experiment? How does this compare with the total number of predicted genes in the yeast genome? 2)(1 point) At the 18.5 hr time point, how many genes were increased in expression relative to the control (0 hour time point) by 2-fold or greater? 3)(3 points) Why are differences in expression measured in fold increase over the control, rather than as an absolute increase in fluorescence signal?

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