BE110Lecture4 - BE 110 Biotransport and Bioreaction...

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Lecture #4 BE 110: Biotransport and Bioreaction Processes
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Prof. Daniel T. Kamei 2 Outline Points to emphasize from Problem Set #1 turned in today Reaction and Michaelis-Menten kinetics Combining reaction kinetics and diffusion
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Prof. Daniel T. Kamei Points to Emphasize from Problem Set #1 Always have an idea of diffusivities and length scales. See that a protein or virus diffusing only 1 cm can take an extremely long time. Need to incorporate convection and/or reduce the length scale. The concentration can be used to determine the average distance between molecules. Biomolecular (or second order) reactions happen faster as the concentration goes up, since the diffusion length scale for the two molecules to find each other decreases. For a unimolecular (or first order) reaction, there is no need for the molecules to find each other. However, the reaction will proceed faster if there is more of the species in the solution, i.e., its concentration is higher. 3
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