Exam 2 Fall 2014 v1 solution

Exam 2 Fall 2014 v1 solution - Exam#2 Bio E 201 Total...

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Exam #2 10/2/2014 Bio E 201 ( / Total Points) Wound Healing 1. The stromal component of a tissue/organ is primarily responsible for its ________structure/biomechanics___________________________ (2 points) 2. ____regeneration_______________________ is a response to injury that results in complete restoration of native structure and function (2 points) 3. _______enzymes____________________ are proteins that catalyze biochemical reactions by lowering the activation energy. (2 points) 4. Coagulation is initiated any time blood comes in contact with anything or than ____endothelial cell__________________________________ (2 points) 5. A blood clot is composed primarily of a linear protein polymer ____fibrin (fibrinogen=1 point)_________________________ that is covalently crosslinked by ______Factor XIIIa (Factor XIII=1 point)_______________________________ (4 points) 6. Heparin released from mast cells forms a complex with ______anti-thrombin III ____________________________ that inhibits thrombin and plays an important role in downregulating the coagulation cascade (2 points) 7. __phagocytosis_____________________________ is the process of internalization and destruction of foreign material and pathogens during the inflammatory phase of the wound healing process (2 points) 8. ____chemotaxis__________________________ is the directed migration of inflammatory cells to a site of injury in response to a concentration gradient of a soluble molecule (2 points) 9. During the proliferative phase, ____re-epithelializaiton _____________________________________ is responsible for restoration of dermal (skin) integrity (2 points)
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10. During the proliferative phase, granulation tissue formation process consists of the recruitment and proliferation of ____fibroblasts______________________________ (cell type) and their synthesis of ____collagen___________________________ (matrix component) (4 points) 11. Angiogenesis is stimulated by ____vascular endothelial growth factor ________________________________________ that is produced and secreted
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