Exam 2 Fall 2014 v2 solution

Exam 2 Fall 2014 v2 solution - Exam#2 Bio E 201 Total...

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Exam #2 10/2/2014 Bio E 201 ( / Total Points) Wound Healing 1. The parenchymal component of a tissue/organ is primarily responsible for its ________specialized biochemical function___________________________ (2 points) 2. ____regeneration_______________________ is a response to injury that results in complete restoration of native structure and function (2 points) 3. _______enzymes____________________ are proteins that catalyze biochemical reactions by lowering the activation energy. (2 points) 4. Coagulation is initiated any time blood comes in contact with anything or than ____endothelial cell__________________________________ (2 points) 5. ______thrombin__________________ is responsible for cleaving fibrinogen to fibrin that then spontaneously self-assembles into a linear polymer. Factor XIIIa then stabilizes these fibrin chains by ______crosslinking_____________________________ (4 points) 6. ____heparin_____________________released from mast cells forms a complex with anti-thrombin III that inhibits thrombin and plays an important role in downregulating the coagulation cascade (2 points) 7. ____neutrophils_________________________ are the primary cell type responsible for phagocytosis during the inflammatory phase of the wound healing process (2 points) 8. ____proteases______________ are responsible for the degradation of other proteins, including the fibrin clot that must be broken down in order to be replaced (2 points) 9. During the proliferative phase, ____re-epithelializaiton _____________________________________ is responsible for restoration of dermal (skin) integrity (2 points) 10. During the proliferative phase, granulation tissue formation process consists of the recruitment and proliferation of ____fibroblasts______________________________ (cell type) and their synthesis of extracellular matrix that is stimulated by
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_____transforming growth factor beta-1____________________ (growth factor) (4 points) 11. Angiogenesis is stimulated by ____vascular endothelial growth factor ________________________________________ that is produced and secreted
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  • Fall '13
  • Webb
  • Angiogenesis, chronic foreign body

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