Wound Healing 2014 (1) - BioE 201 BioE 201 Wound Healing...

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* BioE 201 BioE 201 Wound Healing
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* BioE 201 Why Study Wound Healing Most medical devices must be implanted-inserted into and interfaced with physiological tissue Standard implantation method-open surgery Surgery causes tissue injury-wound healing New surgical methods-minimally invasive surgery- minimize tissue damage / recovery time / functional outcome Almost all medical device implants first experience a wound healing environment The body’s response to the medical device consists of alterations in the wound healing response elicited by the device
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* BioE 201 Responses to Injury Regeneration Complete restoration of native tissue structure and function Wound Healing-most common response to tissue damage-repair process resulting in scar tissue Absence / failure of healing Spinal cord Geometry Pathology
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* BioE 201 Regeneration in Humans Bone Liver Peripheral nerve
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* BioE 201 Characteristics of Scar Tissue Altered biochemical composition- extracellular matrix Deficient biomechanics relative to native tissue
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* BioE 201 Phases of Wound Healing Inflammatory Coagulation-stop bleeding Prevent infection Proliferative
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