Biomaterials-Lecture 1(1)(1) (1)

Biomaterials-Lecture 1(1)(1) (1) - BioE 201 BioE 201...

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* BioE 201 BioE 201 Biomaterials: Properties and Characterization
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* BioE 201 Outline Biomaterials Selection criteria Metals Ceramics Polymers Biodegradable/Bioerodible
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* BioE 201 Biomaterials Definition-A biomaterial is a nonviable material used in a medical device, intended to interact with biological systems (Williams, 1987). Metals Ceramics Polymer s Synthetic Naturally derived
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* BioE 201
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* BioE 201 Selection Criteria Availability / cost effectiveness Ability to be processed into desired form Mechanical properties fatigue strength wear resistance Non-toxic (leachables-degradation products) corrosion resistance Biocompatible Sterilizable Stability / Degradability
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* BioE 201 Metals Metals are (mostly) crystalline solids composed of elemental, positively charged ions in a cloud of electrons High strength and stiffness High conductivity Isotropic properties-mechanical properties are independent of the direction of testing Properties and fabrication well known Relatively bioinert / stable
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* BioE 201 Biomedical Applications of Metals Artificial Joints stainless steel cobalt chromium titanium alloys Heart Valves stainless steel mounts Vascular Stents stainless steel nitinol All metals used as biomaterials are fabricated from alloys that possess increased corrosion resistance relative to base metals
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* BioE 201 Metal Corrosion Metals are rarely found in nature in pure form, usually as oxides (raw ores) Purification requires tremendous energy input Corrosion-degradation of metals through electrochemical reactions, reproducing metallic oxides Corrosion is energetically favorable because it transforms the pure metal back to the lower energy oxidized form
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* BioE 201
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