Hanna Week 4 key - IA Hanna Tran [email protected] Topics...

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IA: Hanna Tran Section: Tue 6-6:50 APM 2301 [email protected] OH: Wed 1PM Hi Thai BIPN 100 PROBLEM SET: WEEK 4 Topics: Conduction Factors Synaptic Transmission Postsynaptic Events Neurotransmitters Summation Long term Potentiation CONDUCTION FACTORS 1. An axon with a ________________ (smaller/ larger ) diameter will have greater conductance—it needs __________ ( less /more) action potentials to traverse a greater distance along the axon. 2. How do action potentials get conducted over long distances? An action potential acts as an above-threshold stimulant to the next portion of the axon, causing the next portion to get depolarized and form its own action potential. This continues down the axon. 1
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IA: Hanna Tran Section: Tue 6-6:50 APM 2301 [email protected] OH: Wed 1PM Hi Thai 3. (a) The __ myelin sheath ___ is a membrane that is made up of __ Schwann cells ___ wrapped around sections of the axon—its purpose is to __ insulate ___ the axon. The bare sections of the axon in between are called the __ nodes of Ranvier ___. In ___ saltatory conduction ___, action potentials seem to __ jump __ from node to node. (b) What is the effect of the myelin sheath on the speed of action potential conduction? Action potential conduction occurs more rapidly along myelinated axons. (c) Demyelinating diseases such as multiple sclerosis inhibit the nervous system from communicating due to disrupted action potential conduction. Explain. Demyelinating diseases result in damaged myelin sheaths, which leak out current, slowing conduction. These areas between the nodes that were previously insulated have no voltage-gated Na + channels, so depolarization can not occur in these areas to sustain an action potential. Normally, the myelin sheath insulates these areas between the nodes, so that the signal that occurs at the node can travel quickly through the insulated region and stimulate an action potential on the next node.
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