Human Physio notes Week 1 - IA Adrian Bahn BIPN 100 Dr...

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IA: Adrian Bahn BIPN 100 – Dr. Fortes 01/04/16 Intro+Overview Membrane Dynamics Diffusion + Osmosis Osmolarity + Tonicity Simple Diffusion Ohm’s Law Fick’s Law Proteins – Channels: always open (leak) and gated Transporters: simple transporters, symporters, and antiporters Ion pumps Physiology is an integrative science, and draws from diverse scientific backgrounds in order to explain the properties and mechanisms of the human body, including but not limited to, biology, chemistry, and physics. You will be expected to do basic algebra and arithmetic without the aid of calculators, such as logarithms of base 10, long division and multiplication, addition and subtraction, and exponents. It is an expansive subject and there will be a lot of memorization, but do not try to memorize everything. Instead, memorize using context and try to understand the material on an abstract and fundamental level, making connections and recognizing patterns to lighten the load. There will be two midterms (Jan 29 and Feb 26), each worth 20% of your total grade and one final (March 18) worth 60% of your total grade. Go to section. Even if you don’t go to lecture and you podcast it, go to section. Go to two, even. I mean it; it’s really important for all of Fortes’s classes. Membranes are essential structures for any living organisms, as they maintain a physical and chemical environment inside the organism that is usually very different to the outside. One of the purposes of selectively permeable membranes in biology
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IA: Adrian Bahn BIPN 100 – Dr. Fortes (which the cell membrane is) is to control the rates of diffusion of molecules in or out of the cell . Diffusion , the gradual dispersion of molecules (in our context usually aqueous, sometimes gaseous), progresses towards equilibrium. Equilibrium means that the flow of molecules one way or the other is equal throughout, and the flow is usually down the concentration gradient mostly through Brownian motion. In other words, molecules tend to move from areas of high concentration to areas of low concentration simply through statistical probability and random collisions. Osmosis is specifically the diffusion of water, which diffuses from low solute concentrations to high solute concentrations. If the previous statement confuses you, think of it as when you add solutes to water, you’re actually diluting the concentration of water. In other words, imagine a U-tube with a semi-permeable membrane, one side containing a 1M solution of glucose, and the other pure water. A 1M solution of glucose in 1L volume has less water molecules per 1L of volume than 1L of pure water (i.e., the 1M solution has a lower concentration of water, the pure water has a higher concentration of water), so some water from the pure water will diffuse to the 1M solution (down the water concentration gradient, but up the solute gradient).
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