bio - Mitochondria are usually depicted as oval double...

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Mitochondria are usually depicted as oval double membrane organelles o Undergo rounds of fusion and fission and their shape can change to be considered tubular 1 There is an outer membrane, an inner membrane and between the two membranes there is an inter membrane space (region) Cristae have a lot of things happening on them Outer mitochondrial Membreane o High lipid, low protein o Contains many ezymes with diverse metabolic functions o Porins are large channel proteins and when open, membrane is freely permeable Inner Mitochondrial Membrane o High protein:lipid ratio 3:1 o Double-layered folds = cristae Increase membrane surface area Contain machinery for aerobic respiration and ATP formation Rich in a phospholipid called cardiolipin o Aqueious compartments of mitochondria Inter-membrane space Matrix High protein Mitochondrial ribosomes Mitochondrial DNA (mtDNA) o Encodes polypeptides that are integrated into the IMM, ribosomes, tRNA Major function of mitochondrion
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Unformatted text preview: o Provide cells with energy (ATP) obtained from glucose o Glycolysis Occurs in the cytoplasm outside the mitochondria o Pyruvic acid oxida±on Occurs en±rely in the mitochondrial matrix o Tricarboxylic acid (TCA) cycle (Kreb Cycle) Occurs mainly in the matrix Oxida±ve phosphoryla±on o ATP synthesis in the mitochondria Step 1 Electron transport and proton pumbing o Generates an electrochemical gradient High energy electrons pass from co-enzymes (NADH and ²ADH2) in the matrix to electon carriers in IMM Series of e-carriers o Respiratory enzyme complexes I, II, III, and IV = Electron Transport Chain o Eventually, low energy electron (e-) transferred to terminal e-acceptor (O2) H2O produced Step 2 Proton movement down electrochemical o Gradient powers ATP synthesis When ATP forma±on is driven by energy released from electrons removed during substrate oxida±on, the process is called oxida±ve phosphoryla±on...
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