L6 graded potential post - Neurons Graded Potentials...

Info icon This preview shows pages 1–10. Sign up to view the full content.

View Full Document Right Arrow Icon
Neurons: Graded Potentials Analyze factors that affect the magnitude and direction (depolarizing or hyperpolarizing) of a graded potential stimulated by an incoming. Analyze factors that affect the relative magnitude of a graded potential as it travels from the signal reception site to the axon hillock. Predict how changes in capacitance and resistance will affect the conduction within an axon Analyze how the cable properties of an axon determine the signal conduction speed of neurons Explain why membrane capacitance affects the generation of new currents but not signal conduction along the axon Calculate the time constant for a change in membrane potential given the membrane resistance and membrane capacitance Thursday, January 22, 2015
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Graded potentials: will they reach the hillock with enough magnitude to generate an AP? Thursday, January 22, 2015
Image of page 2
!"#$%& ( !"#$%& ) !"#$%& * !"#$%&'( +,&- ./" 0"&1./ 2%&3.,&.3 %4 ./"3" * &"#$%&3 ! . " *+,-.*/ 0 " *+,-.*1 0 " *+,-.*2 # . " *+,-.*/ 3 " *+,-.*1 3 " *+,-.*2 45 " *+,-.*1 0 " *+,-.*/ 0 " *+,-.*2 65 " *+,-.*2 0 " *+,-.*/ 0 " *+,-.*1 #5 %7+8 9:: 79;+ <7+ =9>+ :+*?<7 @.*=<9*< Thursday, January 22, 2015
Image of page 3

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
!"#$%& ( !"#$%& ) !"#$%& * !"#$%&'( +,&- ./" 0"&1./ 2%&3.,&.3 %4 ./"3" * &"#$%&3 ! . " *+,-.*/ 0 " *+,-.*1 0 " *+,-.*2 # . " *+,-.*/ 3 " *+,-.*1 3 " *+,-.*2 45 " *+,-.*1 0 " *+,-.*/ 0 " *+,-.*2 65 " *+,-.*2 0 " *+,-.*/ 0 " *+,-.*1 #5 %7+8 9:: 79;+ <7+ =9>+ :+*?<7 @.*=<9*< Thursday, January 22, 2015
Image of page 4
!"#$%&'( !"#$ &'( )(#*&' +,#-&"#& ,. &'(-( / #(01,#- ! . " #(01,#2 3 " #(01,#/ # . " #(01,#2 4 " #(01,#/ 56 " #(01,#2 -"7( "- " #(01,#/ 8(01,# 2 8(01,# / Thursday, January 22, 2015
Image of page 5

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
!"#$%&'( !"#$ &'( )(#*&' +,#-&"#& ,. &'(-( / #(01,#- ! . " #(01,#2 3 " #(01,#/ # . " #(01,#/ 4 " #(01,#2 56 " #(01,#2 -"7( "- " #(01,#/ 8(01,# 2 8(01,# / You can look at the distance (x axis) over which change in membrane potential will decrease to 37% of its original value and figure out which distance is longest. Calculating 37% of 50mv and 20mv is awkward! I prefer to look at the distance (x axis) over which change in membrane potential will decrease to 50% of its original value ( way easier !) and figure out which distance is longest. (Distance over which change in V m (GP) dies down) Thursday, January 22, 2015
Image of page 6
Graded potential decay and the time constant The time it takes the membrane potential to get to its maximal value is determined by what? Figure 4.22 Thursday, January 22, 2015
Image of page 7

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Figure 4.22 Membranes act as capacitors This property causes a delay in the change in V m following current injection Capacitance Thursday, January 22, 2015
Image of page 8
Factors Affecting Capacitance Membrane capacitance ( C m ) depends on two features of the membrane: 1. Membrane surface area: area ( A ) àฏ capacitance 2. Insulating layer thickness ( d ): thickness àฏ capacitance Capacitance is the quantity of charge needed to create a potential difference between two surfaces of a capacitor.
Image of page 9

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 10
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern