MIMM214_ProblemsPackage

MIMM214_ProblemsPackage - 1 Based on this picture of an...

Info icon This preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
1. Based on this picture of an antibody, which of the following statements is FALSE? a. If the molecule is broken below the disulphide bonds no signalling can occur b. If the molecule is broken below the disulphide bonds antigen can be bound c. To use an antibody as a genetic tool to block the function of a specific molecule, we have to break the molecule at the disulfide bond an use only the top region d. If the disulfide bond between the light and heavy chain is broken, no antigen can be bound e. None of the above 2. What is not an implication of class switching? 3. Which of the following statements are false regarding CD4 and CD8 co-receptors? 4. What would you expect in a person who has a dysfunctional P56-Lck? 5. What is a correct statement concerning the relationship between CD28 and CTLA-4? a. CD28 and CTLA-4 both bind CD80 with greater affinity than CD86
Image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
b. CD28 and CTLA both function to enhance T cell activation. c. CD28 activity is up-regulated upon T cell activation whereas CTLA-4 is constitutively active. d. CD28 and CTLA-4 are both co-stimulatory molecules. e. CD28 and CTLA-4 both function to inhibit B cell activation by sequestering B7. Answers: E, B, A
Image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern