CA_Rxns_II - Chemistry Specialist Alicia Hart UC Davis SASC...

Info icon This preview shows page 1. Sign up to view the full content.

CARBOXYLIC ACID RXNS II e) Alcohol Synthesis - Reduction R OH O - NaBH 4 is a weak reducing agent and as such is not strong enough to reduce COOH to OH. R OH f) Bromination: Hell-Volhardt-Zelinsky Rxn OH O NaBH 4 OH O Br 2 Chemistry Specialist: Alicia Hart UC Davis - SASC NR EtOH P (trace) R R Br Br O MECHANISM OH O R P Br Br Br OH O R PBr 2 Br OH O R PBr 2 Br Br O R H OPBr 2 Br O R since P trace we continue on to... HOPBr
Image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: 2 Step 1: Acyl Bromide Synth Step 2: alpha bromination Br O R H OP(OH) 2 Br O R H HO O (another equiv. of starting material) O OH R OH O OH R OH Br O OH R OH Br Br BrH O R H tautomerization H Br OH R Br OH R Br Br OH O R Br Br O H Br Br Br Br Br R R R R 1. LiAlH 4 , Et 2 O 2. H + , H 2 O + OP(OH) 2...
View Full Document

  • Spring '08
  • Nasiri
  • Reducing Agent, Alicia Hart, Acyl Bromide Synth

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern