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In class 3-7-16(1) - Antagonists to Anandamide block the...

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JOY RUN Mice can display symptoms of “runner’s high”—less anxiety and a diminished ability to feel pain—study suggests. After a nice long bout of aerobic exercise, some people experience what’s known as a “runner’s high”: a feeling of euphoria coupled with reduced anxiety and a lessened ability to feel pain. For decades, scientists have associated this phenomenon with an increased level in the blood of β-endorphins, opioid peptides thought to elevate mood. Now, German researchers have shown the brain’s endocannabinoid system—the same one affected by marijuana’s Δ9- tetrahydrocannabinol (THC)—may also play a role in producing runner’s high, at least in mice ( Proc. Natl. Acad. Sci. USA 2015, DOI: 10.1072/pnas.1514996112 ). Antagonists to Anandamide block the “runner’s high in mice even after prolonged exercise
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Practice Problems Enzymes: Introduction, Kinetics & Inhibition
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What term describes the substance that is bound by an enzyme and converted to product? A) inhibitor B) substrate C) coenzyme D) prosthetic group E) cofactor Answer: B
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What term describes an enzyme without its required cofactor? A) holoenzyme B) coenzyme C) isozyme D) apoenzyme E) None of the answers is correct.
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