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Cell Bio Class #4 - Cell Bio Class#4 notes Nucleotide Acids...

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Cell Bio Class #4 notes Nucleotide Acids+ Structure - sugar phosphate backbone - different bit is the nitrogenous base that sticks out (sugars are the pentagons, phosphates are the circles) - base is always attached at #1 C (first C) phosphate always attached at #5 C (last C) The bases: - uracil usually in RNA, not DNA - pyrimidines and purines DNA Strand: - phosphate joined to next sugar by ester link Base Pairing: - antiparallel strands - T always bonds to A - G always bonds to C (stronger due to #H bonds involved, which is three, whereas A/T bonds only have two) - 3’ end matches up to 5’ end - important b/c enzymes read this directionality - double helix of DNA is antiparallel - grooves have an affect on how proteins get in and decide whether to turn genes on or off (DNA space-filling structure slide) Microscopy: - Closest distance b/w 2 distinct objects - resolution can see more detail - resolution limit for human eye is about .2mm (or 200 microns) - better resolution= more clear
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