Exam 3 Answer Key 2

Exam 3 Answer Key 2 - Note: PLEASE USE THIS VERSION. THE...

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Note: PLEASE USE THIS VERSION. THE PREVIOUS VERSION WAS AN OLDER VERSION. Biol 3301 Exam #3 November 29 th , 2007 There are a total of 12 pages in this exam. This exam consists of 36 questions worth a total of 100 points. All questions are multiple choice and there is one best answer for each question. Record your answers on the scantron sheet, and answer only once for each question or you will be automatically marked wrong. Use a #2 pencil. Name_________________________ Peoplesoft ID#__________________________
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1) Transposase is: a. A protein b. A DNA sequence c. A mobile genetic element d. a and c e. b and c 2) McClintock Named the Dissociation element “Dissociation” because a. It would not work in the absence of Activator b. It would create random colored sectors in the aleurone c. It would transpose from the Colored locus d. It would generate controlled chromosome breaks e. All of the above. 3) Which of the following is NOT an error free repair mechanism: a. Nucleotide-Excision Repair b. Translesion DNA Synthesis c. Direct Reversal d. Synthesis Dependent Stand Annealing e. Mismatch Repair 4) You are interested in how E coli can metabolize a novel antibiotic. You have treated E. coli with a mutagen, screened for increased resistance to this antibiotic, identified a mutant, and identified the molecular basis of the phenotype as affecting the promoter region of an interesting gene: Consensus TTGACA–17—TATAAT Wild type promoter TTGTGA—18—TATTAT Mutant Promoter TTGAGA—18-TATAAT Which of the following are good predictions for this mutation? a. This mutation would increase gene transcription b. This mutation would likely be dominant to wild type c. This mutation would create a hypermorph d. Adding extra copies of this gene would increase the resistance to the antibiotic e. All of the above 5) According to the Luria-Delbrück Fluctuation Tests: a. Spontaneous mutations arise from environmental pressure b. Mutations Leading to resistance to Phage T1 appear with high variances in smaller separate cultures compared to a large single culture c. Mutations Leading to resistance to Phage T1 were pre-existing in a culture d. b and c e. a and c 6) You have isolated a dominant mutation in Drosophila that results in purple wings. Interestingly, adding more or fewer wild type copies of the gene into the purple wing mutant background does not change the mutant phenotype. This mutation is a: a. Amorph
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b. Hypomorph c. Antimorph d. Neomorph e. Hypermorph 7) Beta Thalassemia is an autosomal recessive human disorder in which there is a reduced production of hemoglobin. This is a life threatening disorder for infants as it results in severe anemia and requires lifelong transfusions. The frequency of this disease, also known as Cooley’s Anemia, is very high in people from the Western Mediterranean area. In Greece, this disease is occurs in about 1 in every 100 births. Assuming Hardy-Weinberg equilibrium for this trait, the frequency of carriers is: a. 0.01
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Exam 3 Answer Key 2 - Note: PLEASE USE THIS VERSION. THE...

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