Review_Exam3

Review_Exam3 - Chapter 11 List two ways in which enzymatic...

Info iconThis preview shows pages 1–9. Sign up to view the full content.

View Full Document Right Arrow Icon
Chapter 11 • List two ways in which enzymatic catalysis can be regulated. – Inhibitors – Allosteric effectors – Covalent modification – Variations in the level of expression
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Chapter 11 • Which amino acids (including residue number) are involved in the catalytic mechanism of lysozyme? – Asp52 – Glu35
Background image of page 2
Chapter 11 • Which amino acids (including residue number) are involved in the catalytic mechanism of RNase A? –H i s 1 2 – His119
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Chapter 11 • Which amino acids are involved in the catalytic mechanism of serine proteases? –S e r –H i s –A s p
Background image of page 4
Chapter 11 Identify the electrophile in the following list of groups a. ROH b. RSH c. R 2 C=O d. RNH 2 e. Histidine See pg 294 Identify the best enzymatic nucleophiles below a. RO- b. RS- c. RNHC(O)R’ Note: NHC(O) is an amido group d. RNH 3 + e. Histidine See pgs. 294-295, must have lone pair, be able to attack and form a bond, AND must be able to break the bond relatively easily (so, RO- is not one of the best since the RO-R bond is hard to break)
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Chapter 11, review problem • What do enzymes do to increase rates of enzymatically catalyzed reactions?
Background image of page 6
Chapter 11, review problem • What do enzymes do to increase rates of enzymatically catalyzed reactions? • Answer: They decrease the energy of the transition state (i.e. the activation free energy for the reaction, ( G ) ) by preferentially stabilizing the transition state.
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Chapter 11, review problem • What is the substrate and the function of each of the following enzymes?
Background image of page 8
Image of page 9
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 30

Review_Exam3 - Chapter 11 List two ways in which enzymatic...

This preview shows document pages 1 - 9. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online