03 Central Dogma

03 Central Dogma - Central Dogma of Biology From DNA to...

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Central Dogma of Biology From DNA to Genetic Engineering • DNA. Information. – Polymer of Nucleotides – Contains information required for cell to survive and replicate – Enzymes (proteins) can make copies, cut, and paste back together DNA • RNA. Messenger - -from DNA - Protein • Proteins. The workers. What do you need to know to understand Genetic Engineering? http://www. accessexcellence .org/RC/VL/GG/central.html (1) transcription: the code from the gene is copied by creating a piece of messenger RNA (mRNA) that contains the code. (2) translation: the piece of mRNA is used as a template by a ribosome to create the protein. The information from each gene is used to create a protein in two steps Decoding DNA: the “Central Dogma” of Molecular Biology promotor region termination sequence
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Transcription A complement of a gene is created in a piece of mRNA • dsDNA is locally split apart • complementary nucleotides attach to ssDNA (substituting U for T) RNA polymerase strings together the nucleotides into functional mRNA • In RNA, uracil (U) is used instead of thymine (T) How does RNA polymerase “know” where the gene starts and ends?
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This note was uploaded on 02/27/2008 for the course CHEN 1000 taught by Professor Degrazia,j during the Fall '04 term at Colorado.

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03 Central Dogma - Central Dogma of Biology From DNA to...

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