ProblemSet4 - Winter 2014 BME 121 Quantitative Physiology:...

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BME 121Quantitative Physiology: Organ Transport SystemsProblem Set 4Due Thursday March 13th at the beginning of lecture11.Textbook Problem Set 5.3, Problem 2, page 54912.Hypertension and cardiovascular dysfunctionHypertension is a cardiovascular disease that affects ~20% of the population. Oneconsequence of hypertension is increased work required from the heart, thus elevating the riskof heart attack. Another potential consequence is the development of arteriosclerosis due tohigher blood flow rates passing through “stiffer” arteries. We also discussed how bloodpressure is gauged by two numbers, the systolic pressure (PS) and diastolic pressure (PD), andthat there are clinical guidelines for maintaining both below maximum values (<140 mm Hg forPSand <80 mm Hg for PD). With these factors in mind, consider two patients with clinicallydiagnosed hypertension:Patient 1: systolic pressure = 180 mm Hg, diastolic pressure = 80 mm HgPatient 2: systolic pressure = 120 mm Hg, diastolic pressure = 100 mm HgA.

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