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final review - BIOPSYCH FINAL REVIEW Brain Basal...

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BIOPSYCH FINAL REVIEW Brain Basal ganglia—movement Caudate nucleus, globus pallidus, putamen, substantia nigra Limbic system—emotion, learning, memory Fornix, cingulated cortex, thalamus, mammillary body, hippocampus, amygdala, olfactory bulb Cortex—axons and dendrites Ventricles—cerebrospinal fluid in chambers Cingulate Cortex—pain Neurotransmitters Glutamate—major excitatory NT GABA—major inhibitory NT Dopamine—pleasure, reward Mesolimbocortical pathway: VTA to nucleus accumbens, cortex, and hippocampus Mesostriatal pathway: Substantia nigra to striatum (movement, Parkinson’s) Serotonin—mood, anxiety Agonist—bind to and activate receptor Antagonist—bind to and block receptor Non-competitive antagonist—bind to different site but prevents NT from having its effect Partial agonist—activates receptor, but not as well as endogenous agonist Gate Control Theory of Pain Descending information from the brain can gate incoming pain signals in the spinal cord Electrical stimulation of the neurons in the PAG produces analgesia
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