Lecture4_08_Handouts

Lecture4_08_Handouts - Lecture 4 September 4, 2008 Protein...

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1 Lecture 4 – September 4, 2008 Protein structure Some definitions Type of Protein Function Examples Enzyme Pepsin, protein kinase, DNA polymerase, and thousands more Structural Protein Collagen, elastin, tubulin, α -keratin Transport Protein Serum albumin, hemoglobin, Ca 2+ pump, glucose carrier Motor Protein Myosin, dynein, kinesin Storage Protein Ferritin, ovalbumin, casein Signal Protein Insulin, nerve growth factor (NGF), epidermal growth factor (EGF) Receptor Protein Rhodopsin, insulin receptor, adrenergic receptor Gene Regulatory Protein Lactose repressor, homeodomain proteins Special-Purpose Protein Antifreeze proteins (in fish blood), green fluorescent protein, glue proteins (mussels)
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2 Amino Acids are linked together by pepetide bonds to form proteins (or polypeptides) Gray = Carbon Blue = Nitrogen Red = Oxygen White = Hydrogen Proteins are made of a polypeptide backbone with attached side chains Met Asp Leu Tyr SEQUENCE Direction of synthesis [10’s to 1000’s of AAs]
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Lecture4_08_Handouts - Lecture 4 September 4, 2008 Protein...

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