BIO311C_F07_Gene regulation in bacteria

BIO311C_F07_Gene regulation in bacteria - Gene regulation...

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Unformatted text preview: Gene regulation in bacteria Pages 352-356 We will cover • Constitutive and Regulated gene expression • Positive and negative regulation of genes • Operon • Inducible and a repressible operon • Concept of inducer and repressor – Lac operon – Trp operon • Constitutive expression – Always “turned on” • Regulated expression – Turned off till needed by cell Studies of Studies of E. coli E. coli metabolism metabolism This involves interaction of specific regulatory proteins to DNA targets to control transcription TRANSCRIPTION FACTORS E. coli- only 5% transcribed at any one time GENE EXPRESSION is regulated - genes are activated (turned on) when needed and repressed (turned off) when not needed Role of regulatory proteins in transcription regulation Role of regulatory proteins in transcription regulation “Turns on” “Turns off” Negative Regulation • Inducible – Gene off (by repressor), until turned on – by inducer • Repressible – Gene is always turned on, until turned off by a repressor General Organization of an Inducible Gene...
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This note was uploaded on 02/11/2009 for the course BIO 51730 taught by Professor Latham during the Fall '07 term at University of Texas.

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BIO311C_F07_Gene regulation in bacteria - Gene regulation...

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