Male_Reproductive_System_with_px

Male_Reproductive_System_with_px - Male Reproductive System...

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Male Reproductive System : Chapter 22, pages 728 - 771. A. Testis: page 732, figure 22.4 1. Function a. Exocrine: gametogenesis; testicular fluids b. Endocrine: embryonic, puberty, adult c. Temperature control: pampiniform venous plexus
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2. External coverings of testes a. Scrotum: keratinized stratified squamous epithelium without adipose. b. Tunica vaginalis: outer-most layer of testicular capsules; part of serous sac derived from peritoneum; visceral and parietal layers c. Tunica albuginea-dense CT d. Tunica vasculosa: inner-most layer of testicular capsule; loose CT; vascularized 3. Internal Structures a. Mediastinum testis: thickening of tunica albuginea along posterior surface b. Lobuli testi: 250 incomplete compartments separated by septa from mediastinum testis; each contains 1-4 seminiferous tubules 4. Seminiferous Tubules: 0.2mm dia., convoluted; blind-ended or anastomosing loops within lobules a. Germinal or seminiferous epithelium: modified stratified cuboidal epithelium; basal lamina; page 734, figure 22.6 b. Tunic propria: external fibrous tissue; fibroblasts and myoid cells
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c. Supporting elements (1) Sertoli cells (nurse cells): tall, columnar cells with bases on basal lamina and apex at lumen; basal junctional complexes at level apical to spermatogonia; indistinct cell outline; forms blood-testis barrier aa. Function of Sertoli Cells 1. Support, protection and nutritional regulation of developing spermatogonia; protects against immunological attack 2. Phagocytosis of residual bodies 3.Secretion: fluid for sperm transport; androgen binding protein (binds with testosterone and transports into seminiferous tubules); inhibin (suppresses FSH production) (2) Blood-testes barrier aa. basal component: accessible to any blood-borne substance bb. adluminal component: inaccessible to blood- borne substances except those that are taken in by Sertoli cells
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d. Spermatogenic cells: page 737, figure 22.9; page 639, figure 22.10. Comprise germinal epithelium; 4-8 cells deep. Proliferates from basal region to lumen. 2N Chr; 2N DNA 2N Chr; 4N DNA N Chr; 2N DNA N Chr; N DNA (1) Spermatogenesis: spermatogonia to spermatozoa; 3 phases aa. Spermatogonial phase: stem cells divide to replace themselves and to provid committed spermatogonia (1) Spermatogonia A (dark) - Ad (2) Spermatogonia A (pale) – Ap
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