Prophase
-
2 sister identical chromatids
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early mitotic spindle consist of microtubular fibers
-
2 extends between the 2 centrosomes
-
centrosome begin movement (migration) to the opposite poles of the cell (spindle)
-
nucleolus (-i) accumulation of RNA molecules in structural protein molecules
-
assembled large and small ribosomal subunits passing through nuclear cytosol.
Prometaphase
-
microtubule from one pole attaches to kinotochore of one number of a chromatid
pair, and one microtubule from opposite attaches to kinetochore of other member
of pair
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nonkinetochore microtubules
-
cross linking proteins between microtubules from opposite poles
-
alternating pulls by these microtubules toward opposite poles
Metaphase
-
longest stage
-
metaphase – midplane
-
centromeres of all chromatid pairs are aligned on this plane
-
pulls toward opposite poles are precisely balanced
Anaphase
-
shortest stage
-
centromeres divide, chromatid pairs all broken
-
mechanism of centromere division is not well understood
-
enzyme called “topoisomerase” causes centromeres to divide. Begins to reduce
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- Spring '08
- Milton
- Mitosis, Nucleolus, Prophase, RNA molecules, opposite poles
-
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