Pharmacology Drug Cards for HESI - GENERIC NAME Fluticasone TRADE NAME(Flonase Flovent CLASSIFICATION Synthetic steroids of glucocorticoid family of

Pharmacology Drug Cards for HESI - GENERIC NAME Fluticasone...

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GENERIC NAME: FluticasoneTRADE NAME: (Flonase, Flovent)CLASSIFICATION: Synthetic steroids of glucocorticoid family of drugsACTIONS: Fluticasone mimics the naturally-occurring hormone produced by theadrenal glands, cortisol or hydrocortisone. The exact mechanism of action of fluticasoneis unknown. Fluticasone has potent anti-inflammatory actions. Onset: 1-3 wk. Peak: 4-8hr.INDIDCATIONS: Seasonal allergy rhinitisROUTES OF ADMINISTRATION: Intranasal 100 mcg (1 inhalation) per nostril 1-2times daily Max: 4 times dailyUSUAL DOSAGE: Adult and child INH 88-440 MCG twice daily; INH 88-220 mcgtwice daily, max 440 mcg twice daily.ADVERSE REACTIONS: transient nasal irritation, burning, sneezing, epistaxis, bloodymucous, nasopharyngeal itching, dryness, crusting, and ulceration, headache, nausea,vomitingNURSING CONSIDERATIONS: oral and nasal inhalers are not to be usedinterchangeably, use of oral and nasal inhaler provided by manufacturer should becarefully reviewed with patient.
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GENERIC NAME: FLUTICASONE PROPIONATE AND SALMETEROLXINAFOATETRADE NAME: Advair diskusCLASSIFICATION: Anti-asthmatic, combination drugACTION: Fluticasone is an anti-inflammatory corticosteroid; precise mechanismunknown but corticosteroids inhibit multiple cell types and mediator production orsecretion involved in asthmatic response; Salmeterol is a long-acting beta2-adrenergicagonist that catalyzes conversion of ATP to cyclic-AMP; increased cyclic-AMP levelscause relaxation of bronchial smooth muscle and inhibition of release of mediators ofimmediate hypersensitivityINDICATIONS: Long-term, twice-daily maintenance treatment of asthma in clients 12years and older; not for relief of acute bronchospasms ROUTES OF ADMINISTRATION: Inhalation powderUSUAL DOSAGE: One inhalation twice daily about 12 hours apart (morning andevening)ADVERSE REACTIONS: URTI, pharyngitis, headache, upper respiratory tractinflammation, hoarseness/dysphonia, bronchitis, cough, nausea & vomiting
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INTERACTIONS: Beta-adrenergic blockers – block pulmonary effects of salmeterol;also may produce severe brochospasms; diuretics – EKG change and/or hypokalemiamay be worsened; MAO inhibitors/tricyclic antidepressants – action of salmeterol maybe potentiated; administer with extreme caution or within 2 weeks of discontinuation ofMAO inhibitors and tricyclic antidepressantsCONTRAINDICATIONS: Hypersensitivity to any component of the product; primarytreatment of status epilepticus or other acute episodes of asthma where intensivemeasures are neededNURSING CONSIDERATIONS: Do not use Advair Diskus for transferring clientsfrom systemic corticosteroid therapy due to possibility of deaths due to adrenalinsufficiency
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GENERIC NAME: TIOTROPIUM BROMIDETRADE NAME: SpirivaCLASSIFICATION: AnticholinergicACTION: Long-acting antimuscarinic (anticholinergic); in airways, it inhibitsmuscarinic M3receptors at the smooth muscle, leading to bronchodilationINDICATIONS: Long-term once daily, maintenance treatment of bronchospasm
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  • Summer '16
  • adverse reactions, Nursing Considerations, Usual dosage

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