Chapter 15 genetics

Chapter 15 genetics - Chapter 15: Chromosomal basis of...

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Chapter 15: Chromosomal basis of inheritance (2 lectures) I. Morgan’s work with flies A. Early experiment with white-eyed flies B. Are there differences in the genetic make-up of male and female flies? C. Morgan’s explanation of white-eye inheritance. II. Sex-linkage (Page 282+) Problem 1.Red-green color blindness is caused by a sex-linked recessive allele. A colorblind woman marries a man with normal vision. If they have a girl, what is the probability that she will have color blindness? If they have a boy, what is the probability that he will have color blindness? III. Dosage compensation (page 284) A. Mary Lyon’s hypothesis B. When does X-inactivation occur? Problem 2. Anhidrotic ectodermal dysplasia is inherited as a recessive, X-linked (sex-linked) disease that results in a lack of sweat glands. Males who inherit 1 mutant allele (X d ) lack sweat glands, and females who inherit 2 mutant alleles (X d X d ) lack sweat glands. Females who are heterozygotes at this locus (X D X d
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Chapter 15 genetics - Chapter 15: Chromosomal basis of...

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