150-06enzymes[1] - Foundations of Biological Science I...

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Foundations of Biological Science I (BioSci 150) C A + B C + D reactants products A + B C + D substrates products Enzyme Enzymes Many proteins are enzymes enzymes are biological catalysts catalysts speed up reactions vs
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Foundations of Biological Science I (BioSci 150) C Enzymes vs Inorganic Catalysts Inorganic Catalysts Enzymes e.g., Ni, Pl, Ag, etc. e.g., pepsin, trypsin, ATP synthase, ribonuclease, etc. increase rxn rate increase rxn rate unchanged at end of rxn unchanged at end of rxn non-specific highly specific rigid, inflexible flexible - can undergo allosteric change… cannot be regulated can be regulated
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C Potential ( free ) energy Time Reactants A + BC AB + C Products A B C Transition state Figure 3.21 . Activation energy : free energy needed to overcome entropy For the rxn: A + BC AB + C Is this rxn exergonic or endergonic? By binding substrates, enzymes lower the
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This note was uploaded on 04/17/2008 for the course BIO SCI 150 taught by Professor Geraldbergstrom during the Fall '08 term at Wisconsin Milwaukee.

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150-06enzymes[1] - Foundations of Biological Science I...

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