Pathological Gambling Caused by Drugs Used to Treat PDReaction PaperTuhin ChakrabortyThis paper analyzed the use of dopamine agonists to treat Parkinson Disease, and the resulting side effects – namely pathological gambling and other compulsive behaviors. After reading the summaries of the different patients, it became pretty clear that there was a strong correlation between the medication (at the target dose), and the start of compulsive behaviors. The one thing that bothered me as I read it, however, was why each of the patients almost immediately resorted specifically to gambling as opposed to other possible activities.According to the Reuter paper, humans have a baseline homeostatic level of dopamine in the ventral striatum, which normal people maintain by natural reinforcers on a daily basis. However, in pathological gamblers, natural reinforcers are not strong enough, and so drugs of addiction, or gambling, are required to compensate. My understanding, then, would be that the
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