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Chapter9ProblemSet - Karmelo Navalta(kan337 BIO325(51420...

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Karmelo Navalta (kan337) BIO325 (51420) Chapter Nine Problem Set C4) The building blocks of a nucleotide are: a phosphate group, a pentose (5 carbon) sugar, and a nitrogenous base which is either a purine, adenine or guanine, or a pyrimidine, cytosine, thymine, or uracil. Nucleotides are linked together to form a strand of DNA utilizing phosphodiester bonds between the 5’ carbon on a sugar molecule with the 3’ sugar of another nucleotide. This forms the backbone of the DNA or RNA strand C12) The major and minor grooves serve to provide access to certain proteins to bind within these grooves to interact with a particular sequence of bases, thereby regulating gene expression The DNA backbone consist of the phosphates and sugar molecules linked together through the phosphodiester bonds formed between the 5’ and 3’ carbons. If a DNA-binding protein does not recognize a specific nucleotide sequence, I would expect that it recognizes the DNA backbone rather then the grooves because in
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