Chapter13ProblemSet - Karmelo Navalta BIO325 (51420)...

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Karmelo Navalta BIO325 (51420) February 11, 2008 Chapter 13 Problem Set C16) Modified bases within tRNA molecules affect the rate of translation and the recognition of tRNAs by aminoacyl-tRNA synthetases. They can also allow, because of wobble rules, more flexibility in the recognition between a codon and anticodon during the process of translation. For example, the base Inosine in the place of the uracil in the codon UUU (effectively becoming UUI), can bind and recognize three different codons and by proxy three different amino acids. C23) The three stages of translation are initiation, elongation, and termination. Initiation involves the assembly of ribosomal subunits, mRNA, and the tRNA carrying the first amino acid. Elongation involves the sliding of the ribosome along the mRNA which synthesizes the amino acid polypeptide chain. Translation ends with termination when a stop codon is reached and recognized and the polypeptide is released from the ribosome. C24)
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Chapter13ProblemSet - Karmelo Navalta BIO325 (51420)...

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