15 - DNA Structure The substance of heredity Experiment 1...

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DNA Structure The substance of heredity Experiment 1: Griffith infects mice with Streptococcus pneumonia Certain strain of S. pneumonia secrete a polysaccharide capsules, whereas other strains do not. Capsule secreting strains have a smooth colony and those strain unable to secrete a capsule have a rough appearance. + inject the smooth bacteria to the mouse-> die of raising infection, then he take the blood sample and on the plague --. Smooth colony grow on the plague. + inject rough bacteria to the mouse --. Mouse live, Take blood sample and found no colony on the plague. + take the blood sample of smooth colony and boil then inject to the mouse again => the mouse a live => nothing on the plague. + take the live rough cell and dead smooth cell mix together and left for a while , then inject to the mouse => the mouse die, take blood sample one plague => Smooth colony a *** something from the dead smooth bacteria was transforming the rough cell bacteria into smooth cell. Griffith call this process TRANSFORMATION and the identified substance that was causing this to occur was termed the transformation principle. *** Transformation principle acts a lot like genetic material: + Information: the genetic material must contain the information necessary to conduct an entire organisms. The transformed bacteria acquired the information to make a smooth bacteria. + Variation: within any species, a significant amount of phenotypic variability occurs. Variation exist both in the ability to make a capsule and the type that is made. + Replication: since the genetic material is passed from parent to offspring, and from mother to
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This note was uploaded on 04/22/2008 for the course BIO 325 taught by Professor Saxena during the Spring '08 term at University of Texas.

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15 - DNA Structure The substance of heredity Experiment 1...

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