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Flint_and_lead_2022.pdf - ETX10 Class 15: Flint and Lead...

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ETX10Class 15:Flint and Lead
World Health Organizationestimates
Lead perspectives by authoritiesWorld Health Organization1 of 10 major chemicals of public health concern in the WHOChemical Safety AgendaNot possible to establish a tolerable weekly intakeUS Federal Gov’tLead levels are actionable at 10 ug/dL bloodChelation therapy to get the lead out
1996: leaded gasoline was banned by the Clean Air ActExempt: aircraft, racing cars, farm equipment, and marine enginesA voluntary phaseout of lead in gasoline was underwayDecline in lead was correlated to declining lead in peopleLead was replaced by benzene in gasolineOct 2020: Clean Air Act regulations were relaxed by theUS EPA for lead (and arsenic, mercury and benzene)Lead in paintbecame the biggesthuman exposure ofconcern after thisvictory
Age and Dose Determine Toxic Action
Lead adsorptionMost human exposure to lead occurs through ingestion~50% adsorbed in kids~10% adsorbed in adults100% of inhaled lead (PM10) is adsorbedSome lead doesn’t pass throughthe skinshowering in watercontaining lead is safePb absorbed via skinPb in cosmetics

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Term
Fall
Professor
Tjeerdema
Tags
Lead poisoning, Gasoline, Lead perspectives

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