10-1.15_whole_muscle

10-1.15_whole_muscle - 10/15 Whole muscle (cont) -impact of...

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10/15 Whole muscle (cont) - impact of repeated stimulations (APs) -tension is summed -maintained contraction=teatanus -unfused= partial relaxation between stimuli -fuse= no time between stimuli to return Ca - difference between myofibers: 1) Speed of contraction -fast vs. slow (last step 9-8) -differ with respect to mount of ATPase -Hydrolyzing ATP on cross-bridge 2) Mechanisms for synthesizing ATP -oxidative-vascularized, myoglobin -glycolytic-few mitochondria, glycogen stores - Three types of fibers 1) Slow oxidative-low ATPase 2) Fast oxidative- high ATPase; partially glycolytic 3) Fast glycolytic- high ATPase; high glycolytic - Most muscles are mix of types -increase oxidative= red -increase glycolytic= white - Genetic basis -proportion can be modified (sprinted marathoner) -Impact of use/disused : -D muscle structure and/or function -disuse a trophy (disease too) -use-hypertrophy (exercise too) -Aerobic exercise -Increase vascularization -increase number of mitochondria -decrease gatigue -Anaerobic -increase myofibers diameter
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10-1.15_whole_muscle - 10/15 Whole muscle (cont) -impact of...

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