Systematic Lupus Erythematosus

Systematic Lupus Erythematosus - Systematic Lupus...

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Systematic Lupus Erythematosus HSC 411 Rich Held and Jordan Schmidt
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What is Systematic Lupus Erythematosus? Chronic autoimmune disease that is potentially debilitating and sometimes fatal. Immune system attacks the body’s cells and tissue. Most often occurs in the heart, joints, skin, lungs, blood vessels, liver, kidneys and nervous system.
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Where did Lupus Come From? All explanations of the name Lupus originate with the characteristic butterfly- shaped malar rash the disease classically exhibits across the nose and cheeks. The history is divided into three periods The classical Neoclassical Modern
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The Classical Period The disease was first recognized in the Middle Ages and saw the description of the malar rash. The term lupus is attributed to 12 th century physician Rogerius, who described the malar rash.
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Neoclassical Period The Neoclassical period was heralded by Móric Kaposi’s recognition in 1872 of the systemic manifestations of the disease. Useful medication was first found in 1894, when quinine was reported as an effective therapy.
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The Modern Period Began in 1948 with the discovery of the LE cell. In the Middle of the 20 th century Hench discovered the efficacy of corticosteroids in the treatment of SLE.
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Signs and Symptoms Such a broad range of symptoms, it is often misdiagnosed. Symptoms come and go unpredictably Variety of symptoms through out the body. Patients experience periods of activity called “Flare-ups” followed by periods of remission.
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Dermatological Manifestations Malar Rash (see photos) Alopecia, mouth, nasal, and vaginal ulcers Lesions on the skin
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This note was uploaded on 04/17/2008 for the course HST 411 taught by Professor Inugu during the Spring '07 term at Central Mich..

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Systematic Lupus Erythematosus - Systematic Lupus...

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