WK10AssgnPetersO - Application The Pathophysiology of Alzheimers disease NURS 6501N 3 Advanced Pathophysiology Oludotun Peters Walden University August

WK10AssgnPetersO - Application The Pathophysiology of...

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1 Application: The Pathophysiology of Alzheimer’s disease NURS - 6501N – 3- Advanced Pathophysiology Oludotun Peters Walden University August 4, 2016
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The Pathophysiology of Alzheimer’s The Pathophysiology of Alzheimer’s disease disease The plagues are insoluble deposits of proteins and cellular materials. Found outside and around the neurons. Made of beta-amyloid, protein fragment from amyloid precursor protein. The fragments clump together with other neurons, molecules and non-nerve cells. In AD, plaques develop in hippocampus and this hampers thinking and decision making. The plaques begin to form in the brains as early as in the fifth decade of life. 2
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.Continued .Continued Tangles also build up inside the nerve cells. The plaques and tangles built in old people’s brains (Murray, 2012). Are in great number among the people with AD. The cloning of genes, sequence of amino acids and the chemical characterization of amyloid proteins are recent advances (Lu & Bludau, 2011).
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