cogs107cs6

cogs107cs6 - I. Dopamine, Motor control a. Go-nogo theory...

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I. Dopamine, Motor control a. Go-nogo theory of movement: b. Anatomy involved: i. basal ganglia (BG) includes: 1. rostral a. the striatum i. putamen ii. caudate nucleus iii. nucleus accumben b. external segment of the globus pallidus (GPe) c. internal segment of the globus pallidus (GPi) 2. caudal a. subthalamic nucleus (STN) b. substantia nigra (SN) i. pars compacta (SNc) ii. pars reticulata (SNr) iii. pars lateralis (SNl) 3. motor nuclei of basal ganglia: a. striatum (caudate), putamen, globus pallidus b. ventral pallidum and Nacc part of basal ganglia/extended amygdala 4. basal ganglia receives input from cortex, esp primary sensory/motor; also nigrostriatal neurons in SN 5. basal ganglia output to primary/supp motor, thalamus -> premotor 6. loop from primary motor/sensory to putamen -> globus pallidus -> thalamic nuclei -> motor cortex (this is
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feedback to change/adapt movement/sensory info ii. pretty quick transmission from striatum to cortex 1. striatum has inhibitory effect on external and internal
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cogs107cs6 - I. Dopamine, Motor control a. Go-nogo theory...

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