Exam 2 Outline: Main Topics
PVS Problems : Done by Jodi
Respiratory Problems
Upper Respiratory Infection (URI)
Bacterial infections: 25%
Influenza
Common cold
Acute laryngitis
Acute epiglottitis
Respiratory syncytial virus (RSV)
URI: Management
Discussion of antibiotics, oseltamivir, zanamivir
Cough suppressants
Rest
Fluids
Antipyretics
Asthma
Three principle triggers
1.
Allergens and environmental factors
Inhaled substances
Food additives
Medications
2.
Infections
Upper respiratory infection
3.
Psychological factors
Stress
Asthma: Management
Identification of exacerbating factors
Daily monitoring of peak expiratory flow
See online resource on asthma attack trigger diary
Written instructions to manage an acute attack
Education and follow-up
Asthma: Medications
Relievers
SABA
Controllers
Oral systemic corticosteroids
Low, medium, or high-dose ICS
LTRA, cromolyn, nedocromil, or theophylline, zileutin
LABA
Step-up and step-down therapy
Six steps

Chronic Obstructive Pulmonary Disease (COPD)
Obstructive (impaired expiratory flow rate)
Reversible
Asthma
Irreversible
Chronic bronchitis and emphysema
Restrictive (reduced lung volumes)
Musculoskeletal disorders
Tumors
Lung resection, ILD
Chronic Obstructive Pulmonary Disease (COPD) (cont’d)
“Blue bloaters”
Chronic bronchitis and pulmonary hypertension
Edema, cyanosis, polycythemia
“Pink puffers”
Emphysema, severe dyspnea
Relatively normal ABGs
“Barrel chest”
COPD: Objective Findings
AP/lateral chest diameter 1:1
Distant breath sounds
End-expiratory wheezes
Prolonged exhalation
Neck vein distension
Pedal and ankle edema
Clubbing
Fatigue
COPD: Diagnostic Tests
PFTs
FEV
1
/FVC ratio <70% diagnostic for COPD
Chest x-ray (although normal in early COPD)
Chest CT
CBC with diff, blood chemistry, alpha
1
-antitrypsin
Sputum with Gram stain
ECG
COPD: Pharmacological Therapy
Inhaled beta-2 agonist bronchodilators
Inhaled anticholinergic bronchodilators
Corticosteroids
Xanthines
Antibiotics
Diuretics
Mucolytics and expectorants
COPD:
Requirements for Home Oxygen
PaO
2
of 55 mm Hg or less
Oxygen saturation below 85%

A PaO
2
of 55 to 59 mm Hg if erythrocytosis (HCT of 56% or more), cor pulmonale (P wave more than 3
mm in leads II, III, and aVF), edema, or CHF
Goal on 1-2 L/min for 15 hours day is O
2
sat. of 90% or PaO
2
of 60 mm Hg
COPD: Patient Education
Smoking cessation
Yearly influenza shot and every 5 year pneumovax
Physical rehabilitation
Support groups
Teach pursed-lip breathing and O
2
therapy
Assess for depression and treat if present
Discuss advance directives
Community-Acquired Pneumonia (CAP)
Streptococcus pneumoniae, Haemophilus influenzae, Legionella pneumophila, Staphylococcus aureus
Viral pneumonia
Mycoplasma
