Grignard Lab

Grignard Lab - Name: John Conkle Drawer: T18B Date:...

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Name: John Conkle Date: 10/08/07 Drawer: T18B TA: Harpreet Experiment 8: Grignard Reaction Purpose The purpose of this experiment is to learn about Grignard reactions by allowing the nucleophilic Grignard reagent to react with the electrophilic benzophenone to form the tertiary alcohol triphenylmethanol. Theory The main idea in this lab deals with the understanding of Grignard reagents and their importance to science. A Grignard reagent is a magnesium based molecule that is strongly nucleophilic and will attack an available carbonyl group to form a specific alcohol, either primary, secondary, or tertiary. Because of its properties as a strong nucleophile it is very useful in forming other organic materials such as ketones, alcohols, and esters as well. Also, because of its carbon-metal bond, it is classified in a large group of molecules known as organometallic molecules. In this reaction, the addition of bromobenzene to magnesium creates the Grignard reagent, phenyl magnesium bromide, which carries the qualities described above and reacts to form the tertiary alcohol
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This note was uploaded on 04/23/2008 for the course BIO 152 taught by Professor Mccletchie during the Fall '08 term at Kentucky.

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Grignard Lab - Name: John Conkle Drawer: T18B Date:...

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