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SLFinalgenetics - 1 Hemophilia is caused by an X-linked...

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1. Hemophilia is caused by an X-linked recessive allele. In the pedigree shown below which two individuals in the pedigree must be carriers of hemophilia? A. I-1 and II-1 B. I-4 and II-2 C. II-1 and II-2 D. III-2 and III-3 2. A single gene in humans causes blood to be either rhesus positive (dominant allele) or rhesus negative (recessive allele). A woman with rhesus negative blood has already had a child with rhesus positive blood. There could be complications during pregnancy if she has another child with rhesus positive blood. What is the probability of this, if the father is the same, and if his mother is known to have rhesus negative blood? 3. What is a sex-linked gene? 4. What is always a difference between the alleles of a gene? 1
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5. Hypophosphataemia is a disorder involving poor re-absorption of phosphate from glomerular filtrate in humans. It shows a sex-linked dominant pattern of inheritance as illustrated in the following pedigree. Which row in the table correctly identifies the genotypes of individuals 1 and 2? Individual 1 Individual 2 A. X H X h X H Y B. X h Y X H X H C. X h Y X H X h D. unaffected affected 6. What is a karyotype?
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