Com3Table[2]

Com3Table[2] - Table 3.1. Associated gene expression...

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Table 3.1. Associated gene expression patterns and function Stock # Lethality Embryonic expression Larval GFP/Xgal adultGFP/L ethal Phase Related genes (from flybase)Where and what stage gene is expressed? Molecular Function of Protein 103679 lethal cns + pns (a large subset), wing, haltere Xgal:sg, fb, mt, epi Lethal Phase:earl y pupal 1 dsf 2 Gpdh 3 CG9044 1. larva larval brain , embryonic/larva l salivary gland pupa anterior protocerebral neuromere pupa | pharate adult adult brain 2. NA 3. NA 1. a. A ligand-dependent receptor found in the nucleus of the cell b. The function of binding to a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. c. Combining with a steroid hormone to initiate a change in cell activity. 2. Catalysis of the reaction: sn- glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+. 3. NA
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103680 semi lethal scattered cells X gal : sg NA 1 CG13218 2 skf 1. NA 2. larva ( embryonic/larval salivary gland , larval brain ), pupa ( adult brain , anterior protocerebral neuromere ). 1. NA 2. protein binding ; guanylate kinase activity ;
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103681 NA a small # of cells X gal : sg, fg, fb 1 ATPCL 2 CG8370 1. NA 2. NA 1. a. Catalysis of the reaction: ADP + phosphate + acetyl- CoA + oxaloacetate = ATP + citrate + CoA b. Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring. 2. Used for the annotation of gene products whose function is not known or cannot be inferred
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lethal cns midline X gal : sg Lethal Phase: larval or embryo 1 Rab-RP1 2 CG8026 1 NA 2 NA 1 GTP binding ; ATP binding ; hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides ; protein kinase activity ; GTPase activity ; 2 carrier activity ; binding ; folic acid transporter activity ; 103688 103691 103692 103693 103694
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This note was uploaded on 04/24/2008 for the course AH 54 taught by Professor Baker during the Spring '08 term at UCLA.

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Com3Table[2] - Table 3.1. Associated gene expression...

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