ENGR213_lecture4

ENGR213_lecture4 - Immune Response Lecture 4 The Immune...

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Immune Response Lecture 4
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The Immune System  Immune System is a collection of mechanisms that  constitutes the physiological defense by which the  the host’s body recognizes “itself” and foreign  matter, and it destroys or neutralizes foreign  matter both living and non-living. 
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The Immune System; Some Key Nomenclature Innate Immune Response  --  barriers formed by skin, mucosa,  antimicrobial molecules and phagocytes… not specific for pathogens Adaptive Immune Response  --  Response of a vertebrate immune system to  a specific antigen that typically generates immunological memory Lymphoid Organs  --  Organs involved in the production or function of  lymphocytes, such as thymus, spleen, lymph nodes, tonsils and adnoids Thymus  --  In the upper part of the chest. It consists of mature lymphocytes  that eventually migrate to the blood and endocrine cells that secrete  hormones collectively called thymopoietin. It’s size changes with age and  grows until puberty and then it is gradually replaced with fatty tissue. Lymph node  --Nodes scatter the lymph vessels. Where antigens in the  lymph encounter Lymphocytes. Large clusters of lymphocytes, lymphatic  nodules. Also contain many macrophages and dendritic cells.
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Pathogens  --  An organism or agent that causes disease Antigen  --  Molecule that is able to provoke an immune response. Leukocytes  -- white blood cells, lymphocytes, neutrophils,  eosinophils, basophils, and monocytes. Lymphocytes  --  Type of white-blood cell responsible for the  specificity of the adaptive immune system, i.e., T and B cells Dendritic Cells  --  cell derived from bone marrow, in Lymphoid and  other tissue, responsible for phagocytosis of particulate material.   Neutrophil --  white blood cell that is specialized for uptake of  particulate material by phagocytosis and which enters tissues that  become infected or inflamed. Eosinophil -- 
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This note was uploaded on 04/24/2008 for the course ENGR 213 taught by Professor Clague during the Winter '08 term at Cal Poly.

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ENGR213_lecture4 - Immune Response Lecture 4 The Immune...

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