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the-free-living-pathogenic-amoeba-1.pdf - THE FREE LIVING...

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THE FREE LIVINGPATHOGENIC AMOEBACARL JETHRO G. DELLOSA,RMT
OBJECTIVES
NAEGLERIA FOWLERIACANTHAMOEBA
NAEGLERIA FOWLERI
TWO MORPHOLOGIC FORMSAMEBOIDFLAGELLATE
AMEBOIDBLUNT PSEUDOPODLOBOSEMONOPSEUDOPODIUM
FLAGELLATEDPEAR SHAPE WITH 2 ANTERIORFLAGELLATES
EPIDIMEOLOGYMost reports are from the USA and India.Very rare - estimated at 1 in 2.6 millionexposed individuals.Most cases in the USA have occurred insouthern states
PRIMARY AMOEBIC ENCEPHALITISPAM is caused byN. fowleriacute, rapidly progressive CNSinfection, which is usually fatal.swimming in contaminated warmwater
PresentationSymptoms- headache, photophobia, nausea andvomiting.Signs -pyrexia, neck stiffness and localising signs - eg, cranialnerve palsies when encephalitis develops. Patients can present ina comatose state.As the amoeba causes extensive destruction of brain tissue,dramatic neurological presentations occur - eg, fitting, loss ofbody control, seizures, and hallucinations.
DIAGNOSISFBCCT SCANBIOPSYPCRCSF
CLINICAL MANIFESTATIONS
LIFE CYCLE
TREATMENTAMPHOTERICIN BCLOTRIMAZOLEAZITHROMYCIN
PREVENTIONCHLORINATION OF SWIMMINGPOOLS
ACANTHAMOEBA

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Term
Fall
Professor
N/A
Tags
Contact lens, Keratitis, positive Babinski s sign

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