PS%201 - BIOE 322/BIOS 332 Fundamentals of Systems...

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Page 1 of 2 BIOE 322/BIOS 332 Fundamentals of Systems Physiology Spring 2008 Problem Set #1 DUE : W 1/23/08 1. Molly is a 75-year old widow who lives alone. For 2 days, she had a fever and chills and stayed mostly in bed. On rising to go to the bathroom, she felt dizzy, fainted, and fell to the floor. Molly quickly regained consciousness and managed to call her son, who took her to the emergency room, where a diagnosis of orthostatic hypotension was made. Orthostasis literally means to stand and hypotension refers to low blood pressure. Orthostatic hypotension is a significant drop in blood pressure on standing. When a person changes position from lying down to standing, blood “pools” within the veins below the heart because of gravity, and less blood returns to the heart. Consequently, blood pressure decreases because the heart has less blood to pump. Although orthostatic hypotension has many causes, in the elderly it can be due to age-related decreased neural and cardiovascular responses. Dehydration can result from decreased fluid intake while feeling ill and from sweating as a result of a fever. Dehydration can decrease blood volume and lower blood pressure, increasing the likelihood of orthostatic hypotension. Q1. Describe the normal response to a decrease in blood pressure on standing.
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PS%201 - BIOE 322/BIOS 332 Fundamentals of Systems...

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