2008 Exam 3 Answers

2008 Exam 3 Answers - Bio2600: Introduction to Cell Biology...

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Bio2600: Introduction to Cell Biology April 3, 2008 Exam 3 Section 1: Complete each of the following sentences with one of the two words found in the square brackets [A. / B. ]. 1. For reproduction of an organism, it is more important that DNA repair mechanisms are operating correctly in [A. germ cells/B. somatic cells]. 2. Activation of (A. Receptor tyrosine kinases/ B. receptor serine-threonine kinases) can lead to activation of SMAD proteins. 3. Many of the antibiotics in use today selectively inhibit bacterial [A. translation/ B. transcription]. 4. In eucaryotic cells, t he assembly of the general transcription factors begins with the binding of the factor [A. TFIID/B. TFIIH] to DNA, causing a dramatic local distortion in the DNA. 5. DNA polymerase adds nucleotides to the [A. 5'-phosphate/B. 3'-OH] group of the growing strand. 6. Hydrolysis of GTP by a G-protein is prevented by [A. cholera toxin/B. purtussis toxin] binding to the alpha subunit. 7. [A. Heterochromatin/B. Euchromatin] is an area of a chromosome more accessible to transcription machinery. 8. H istone [A. acetylase/B. deacetylase] is an enzyme that modifies histones and renders the DNA more accessible to general transcription factors. 9. When bidirectional rep lication forks from adjacent origins meet, a leading strand always runs into [A. a lagging strand/B. a leading strand]. 10. A string of nucleosomes can coil up to form a (A. 50 nm/ B. 30 nm) chromatin fiber. 11. The human genome is co mprised of 23 pairs of chromosomes, which means that each cell has (A. 23/B. 46) centromeres. 12. A small hydrophobic signaling molecule would likely bind to a receptor [A. in the cytosol/B. in the cell membrane]. 13. The [A. large/ B. smal l] subunit of a ribosome is the first to interact with new mRNAs. 14. The anti-codon ACC recognizes the codon [A. UGG/ B. GGU]. 15. Many bacterial genes contain a region known as a(n) [A. operator/B. promoter] to which a specific gene regulatory protein (not sigma) binds. Section 2: Multiple Choice. Find the one best response to answer each question. Page 1, v3
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16. Telomeres A. are tri-nucleotide repeats at each end of a chromosome. B. allow replication of each chromosome to the very tip because a final primer is not required. C. protect the genomic information by moving the chromosome ends away from critical genes. D. A and C E. A, B and C 17. The sigma subunit of b acterial RNA polymerase A. recognizes bacterial and eukaryotic promoter sites in the DNA. B. contains the catalytic activity of the polymerase. C. remains part of the polymerase throughout transcription of an operon. D. recognizes bacterial promoter sites in the DNA. E. recognizes transcription termination sites in the DNA. 18.
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2008 Exam 3 Answers - Bio2600: Introduction to Cell Biology...

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